There are ten playable races to choose from: Argonian: A versatile race, they receive many bonuses that are useful for thieves yet also get boosts to Alteration and Restoration their rapid-healing daily ability is also better suited to combat than stealth. These choices have no effect on gameplay.
Neither sex will stop you from any spouse choices. As movement speed is a function of height, it is indirectly affected by sex. For certain races, your height is dependent on your sex. As there are more male shopkeepers and enemies, female characters garner a greater benefit from these effects. Also, there is a quest that provides you with the added bonus of dealing more damage to the opposite sex. However, NPCs will address you differently, and may treat you differently, depending upon your sex (the Allure perk in Speech skill allows you to get 10% better prices with the opposite sex). The factors that you must decide upon are: